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Market Crux Initiates Coverage On Autonomix Medical, Inc. (NASDAQ: AMIX) Starting Right Now—Friday Morning, June 27, 2025
Here's What We Can Tell You About (AMIX) — So Far…
$100B Target Area: Focused On Pain, Nerve Signals, And Stimulation
Patent Portfolio: Recent Patent Grant Adds To 120+ Issued And Pending
There's Less Than 2.2M Shares Available In The Public Float Which Could Set The Stage For Big Swing Potential If Demand Begins To Shift.
Analyst Targets: With One That Suggests Over 1,300% Upside Potential
From Current Levels
Get (AMIX) On Your Screen This Morning While It's Still Quiet… June 27, 2025 Early Friday Coverage | See Why (AMIX) Tops Our Watchlist Right Now Dear Reader,
Momentum is building this morning—and (AMIX) is right in the middle of it. Autonomix Medical, Inc. (NASDAQ: AMIX) just made an approximate 17% early move, reaching $1.47 off of yesterday's $1.25 close. It cleared its 5-day and 20-day moving averages, with higher levels still on the radar—and we're keeping (AMIX) locked on our screen right now. Behind this move is breaking news: Autonomix just secured a new U.S. patent, strengthening its position in precision, nerve-focused care. The newly granted U.S. Patent No. 12,279,889 B2 covers advanced systems for locating and monitoring neural signals before, during, and after neuromodulation or denervation procedures. It also includes tools for accessing small vessels to treat cancer-related pain, expanding Autonomix's reach across chronic pain, hypertension, cardiac care, and neurological disorders. CEO Brad Hauser described this patent as a milestone for delivering less invasive, more effective treatments while growing the company's IP portfolio, now at over 80 issued patents. Looking ahead, Autonomix plans to submit an IDE and begin U.S. clinical trials in 2025 to pursue approval for its catheter-based sensing and RF ablation system aimed at treating pancreatic cancer pain. Their platform is designed to replace risk-heavy pain management with a precision-guided, sense-treat-verify method powered by its proprietary microchip sensing array. If you haven't pulled it up yet, now is the time to get (AMIX) on your screen—this is happening right now. The wait is over—and now it's time to pull up the profile we've been keeping sealed until this very moment. The company is Autonomix Medical, Inc. (NASDAQ: AMIX)—and based on everything lining up right now, it just became our next potential breakout idea. According to MarketWatch, (AMIX) has fewer than 2.2M shares in its public float—placing it among the tightest floats currently listed on Nasdaq. When a company has a float this small, it doesn't take much for it to see big swing potential, when demand begins to shift. Just this month, two institutional analysts released coverage with head-turning upside targets: - On June 12, Maxim Group's Anthony Vendetti reiterated coverage on (AMIX) with a $5 target, based on the strength of its early clinical data and medical platform. Which suggests over 290% upside potential from recent levels.
- Then yesterday, on June 26, Jeffrey Cohen of Ladenburg Thalmann raised the bar dramatically—publishing a note assigning an $18 target. From where (AMIX) began the day, this suggests more than 1,300% upside potential.
At the same time, RSI readings across the 9, 14, and 20-day timeframes are hovering in the mid-30s—a technical zone that has historically signaled early-stage momentum for potential trend reversals. Keep reading to see why (AMIX) has our attention now—and what may come next. (AMIX) Is Rewiring the Standard of Pain Care—Literally
See Company Presentation Deck Here (AMIX) is working to transform how pain is addressed in some of the most difficult medical cases—starting with advanced cancers like pancreatic. Backed by strong early clinical results, a growing patent portfolio, and a leadership team with a proven track record, Autonomix is developing a new kind of treatment system that goes far beyond today's standard methods. At the center of their platform is a specialized device powered by a proprietary microchip—built to detect and interpret nerve activity with remarkable accuracy. This chip is small enough to get close to the source of pain and smart enough to guide real-time treatment, allowing doctors to pinpoint overactive nerves, treat them directly, and confirm success in one seamless procedure. 
Unlike current techniques that rely on indirect targeting or blind ablation, Autonomix's system gives physicians real-time feedback—offering greater confidence and control during treatment. This targeted approach may help reduce complications, lower opioid use, and open doors to broader nerve-related care. FDA Submission Timeline in Sight as (AMIX) Prepares for Platform Expansion
Autonomix is tackling one of cancer care's most urgent challenges: severe, hard-to-treat pain. In its first-in-human trial, 100% of pancreatic cancer patients treated through a specific access point responded, with many feeling relief within 24 hours. After 4–6 weeks, 73% had stopped using opioids—without any serious complications. What sets the company apart is its precision-based approach. Unlike traditional methods that rely on broad targeting or blind ablation, Autonomix's system identifies and treats overactive nerves in real time—then confirms success on the spot. 
It's smarter, faster, and more focused. Now, the company is expanding its platform to address pain caused by other visceral cancers, including liver, bile duct, and gall bladder. The new study begins in Q2 2025, with a 2026 FDA submission still in sight—positioning Autonomix to potentially redefine how nerve-driven pain is managed across some of medicine's most difficult cases.
A Platform Built by Veterans
Autonomix isn't just betting on technology—it's backed by a leadership team with a track record of execution. CEO Brad Hauser previously led exits totaling over $3B, including a $550M acquisition by AbbVie and a $2.4B sale to Allergan. Other key executives and co-founders also bring deep medtech experience and have led companies through commercialization, regulatory approval, and large-scale acquisitions. With more than 120 issued and pending patents, Autonomix is working to secure a durable IP moat around its proprietary systems and signal-processing technologies. Recent Headlines
Over the past several weeks, (AMIX) has released a series of updates that underscore both the momentum behind its clinical program and the growing institutional confidence in its proprietary platform. June 2025: Clinical Expansion Approved
Autonomix received Ethics Committee authorization to begin PoC 2, the next phase of its clinical program. This study expands beyond pancreatic cancer to include liver, bile duct, and gall bladder cancers—conditions tied to intense nerve-driven pain. With enrollment expected to begin soon, (AMIX) is now targeting a broader clinical field that could double its reach. May 2025: Key U.S. Patent Granted
In a major milestone, Autonomix was granted U.S. Patent No. 12,257,071, covering its real-time nerve-mapping and ablation technology. The patent protects innovations like embedded sensors, adaptive controls, and full-system integration—further strengthening (AMIX)'s edge in treating nerve-driven conditions with precision and minimal invasiveness. April–May 2025: Breakthrough Clinical Results
Autonomix shared strong results from its first human trial treating pancreatic cancer pain. 100% of targeted patients responded, with pain relief starting in 24 hours, and 73% off opioids by week six. These results confirmed both the safety and power of the company's "Sense, Treat, Verify" approach—and set the stage for its upcoming expansion into other high-need areas. Positioned for the Future
Autonomix is targeting a total combined market potential exceeding $100B, with focus areas spanning pain management, neurostimulation, and visceral nerve-related indications. Its minimally invasive system stands out in a field crowded by blind ablation procedures and signal-blind diagnostics. As new trials begin and technical progress continues, (AMIX) remains a name worth watching in the emerging class of neural-targeted precision therapies. Official Coverage Starting: 7 Reasons Why (AMIX) Is Topping Our Watchlist
This Morning—Friday, June 27, 2025….
1. Targeting $100B Space: With focus areas across pain management, neurostimulation, and nerve-focused conditions, (AMIX) is positioned in segments exceeding $100B combined.
2. Tiny Public Float: With fewer than 2.2M shares in circulation, (AMIX) has the potential for big swings if demand begins to shift. 3. Analyst Targets: In June 2025, (AMIX) received analyst targets of $5 (Maxim Group, approx. 290% upside potential ) and $18 (Ladenburg Thalmann, approx. 1,306% upside potential)—pointing to strong institutional interest. 4. Oversold Technicals: RSI levels for (AMIX) have hovered in the mid-30s across multiple timeframes—a setup that has historically signaled early-stage momentum for potential trend reversals. 5. Trial Results Delivered: Early data from (AMIX)'s first-in-human study showed a 59.2% average reduction in pain and 73% of patients eliminating opioid use within 4–6 weeks. 6. Patent Momentum Building: A newly granted U.S. patent in May 2025 strengthened (AMIX)'s hold on its core catheter-based system, adding to a portfolio of 120+ issued and pending patents. 7. Platform Expansion Underway: As of June 2025, (AMIX) secured approval to begin a follow-on clinical study targeting visceral cancers that could double its clinical reach. Get (AMIX) On Your Screen This Morning While It's Still Quiet…
Just remember—there's fewer than 2.2M shares in (AMIX)'s public float, which could set the stage for big swing potential if demand begins to shift. Add in recent analyst targets from Maxim Group ($5) and Ladenburg Thalmann ($18), reflecting approximately 290% and 1,306% upside potential, and we're looking at a situation that demands attention. Backed by real clinical data, fresh patent momentum, a next-phase trial now underway, and RSI levels which have historically signaled the potential for early-stage trend reversals—Autonomix Medical, Inc. (NASDAQ: AMIX) is positioning itself in a high-value space that could top $100B across pain management, neurostimulation, and nerve-targeted care. Now's the time to get (AMIX) on your screen. (AMIX) made an approximate 17% early move, reaching $1.47 off of yesterday's $1.25 close, clearing its 5-day and 20-day moving averages. With higher technical-levels still on the radar—and we're keeping (AMIX) locked on our screen right now. Also—my next update could be out at any moment—so keep your eyes peeled. Sincerely,
Gary Silver
Managing Editor, Market Crux
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