| From MAIA's closing valuation on Wednesday, this $10.27 target suggests an upside potential of over 500%!
Critical Report Info:
Valuation: With continued positive readouts, the initiation of THIO-104 (Phase 3 study) remains a key potential valuation catalyst, marking progression towards controlled clinical validation and potential registration. We have revised our valuation model to reflect the recent Q3 financial results, updated share count, and reassessed comparable company analysis, reiterating our valuation of $10.27 per share contingent on successful execution by the company.
#2. Another Major Analyst Target Suggest Serious Upside Potential (Triple-Digit!).
Noble Capital Markets - $14.00 Target - (Potential upside of 800+% from Wednesday's close.)
Key Report Details:
Conclusion. Roche becomes the third pharmaceutical company to make a supply agreement with MAIA to test a checkpoint inhibitor in combination with THIO. We believe this shows that potential partners have noticed the data showing improved overall survival (OS), progression free survival (PFS), and the side effect profile. Clinical data from the three of the eight approved checkpoint inhibitors could make bidding for a marketing partnership more competitive. We are reiterating our Outperform rating and $14 price target.
#3. A Key Confidence Boost Appears As Insiders Scoop Up Shares.
MAIA Biotechnology, Inc. recently announced that its CEO and board members purchased approximately 182,445 shares of company st-ock on the open market, signaling strong insider confidence.
CEO Vlad Vitoc acquired 94,300 shares, while directors Cristian Luput and Stan V. Smith bought 88,145 shares collectively.
Their purchases demonstrate belief in MAIA’s cancer-therapy pipeline—particularly the promising ateganosine immunotherapy, which achieved a 38% response rate and 17.8-month overall survival in Phase 2 trials—positioning MAIA for impactful future growth and shareholder value creation.
#4. MAIA Has A Relatively Low Float (Volatility Potential May Be Explosive).
Sporting a float of roughly 32.18Mn shares, according to Yahoo Finance, volatility potential could pop up in a flash.
#5. MAIA Biotechnology Showcases Significant Success Strengthening Survival Statistics In Study.
MAIA Biotechnology reported strong Phase 2 THIO-101 results in advanced NSCLC, showing ateganosine plus cemiplimab achieved median progression-free survival of 5.6 months—over twice the standard of care’s 2.5 months—and median overall survival of 17.8 months.
Two patients completed 33 treatment cycles, highlighting durability and low toxicity.
CEO Vlad Vitoc emphasized the significance of extended dosing and superior efficacy as the expansion trial began enrolling in July 2025, aiming to further validate ateganosine’s potential as a breakthrough treatment option for patients with few remaining therapeutic alternatives.
#6. Major Advancement Marks MAIA Biotechnology’s Monumental Milestone In Medical Innovation.
MAIA Biotechnology received a $2.3Mn NIH grant to expand its THIO-101 Phase 2 trial of ateganosine for third-line advanced non-small cell lung cancer (NSCLC).
The funding supports U.S. patient enrollment from 2025 to 2027 following FDA IND clearance.
Early results show median overall survival of 17.8 months versus the 5–6 months seen with standard chemotherapy, underscoring ateganosine’s promise as a breakthrough immunotherapy.
#7. MAIA Biotechnology Embraces Strategic Crypto Strategy Development For Long-Term Growth Potential.
MAIA Biotechnology, Inc. announced a forward-thinking digital asset treasury strategy, authorizing up to 90% of its liquid assets to be held in premier cryp-to-currencies, including Bit-coin, Eth-er-eum, and U-S-D Coin.
The initiative reflects MAIA’s commitment to innovation, value growth, and portfolio diversification.
Plans include forming a Digital Assets Advisory Board to guide prudent in-vest-ment decisions and ensure cy-ber-security, risk management, and compliance remain top priorities. -----
MAIA Biotechnology, Inc. (NYSE American: MAIA) takes back over the top spot on our watchlist Thursday.
When updates pop up, I'll get them out quickly. Talk shortly.
All the best, Dane James Editor Market Pulse Today
(Remember: St-ock Prices Could Be Significantly Lower Now From The Original Dates I Provided.)
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Pursuant to an agreement between Thousand Sun Media LLC and TD Media LLC, Thousand Sun Media LLC has been hired for a period beginning on 12/10/2025 and ending on 12/11/2025 to publicly disseminate information about (MAIA:US) via digital communications. Under this agreement, Thousand Sun Media LLC has been paid seven thousand five hundred USD ("Funds"). To date, including under the previously described agreement, Thousand Sun Media LLC has been paid sixty four thousand USD ("Funds"). These Funds were part of the funds that TD Media LLC received from a third party who did not receive the Funds directly or indirectly from the Issuer and does not own st-ock in the Issuer but the reader should assume that the clients of the third party own shares in the Issuer, which they will liquidate at or near the time you receive this communication and has the potential to hurt share prices.
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